Sunday, 22 March 2026

OPERON OVERDRIVE: THE LAC SWITCH Game

๐Ÿงฌ Operon Overdrive: The Lac Switch

Master the most heavily tested concept in molecular biology! Analyze the cellular environment and the genotype, then instantly predict the expression level of the lac operon.

  • ๐Ÿ”ด OFF: Repressor is bound. (Happens when Lactose is ABSENT).
  • ๐ŸŸก BASAL (Low): Repressor is removed, but no CAP-cAMP. (Happens when Lactose is PRESENT, but Glucose is also PRESENT).
  • ๐ŸŸข HIGH (Max): Repressor removed AND CAP-cAMP bound! (Happens when Lactose is PRESENT, and Glucose is ABSENT).
  • ๐Ÿšจ EXAM TRAP MUTANTS:
    • lacI(s) = Super-repressor. It NEVER falls off. Transcription is ALWAYS OFF.
    • lacO(c) = Operator mutant. Repressor CANNOT bind. It will transcribe even without Lactose!
Score 0
Combo x1
Time 30
P O lacZ lacY lacA
Glc: HIGH
Lac: LOW
WT
System Ready. Awaiting Initialization.

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